Dinges Jurgen, Lamberth Clemens (Ed.) Bioactive Heterocyclic Compound Classes: Pharmaceuticals

Wiley-VCH Verlag & Co., 2012. — 354 p. — ISBN: 3527333959.The chemistry of heterocycles is an important branch of organic chemistry. This is due to the fact that a large number of natural products, e. g.
hormones, antibiotics, vitamins, etc. are composed of heterocyclic structures.The Significance of Heterocycles for Pharmaceuticals and Agrochemicals
Neurological Disorders
Tropane-Based Alkaloids as Muscarinic Antagonists for the Treatment of Asthma, Obstructive Pulmonary Disease, and Motion Sickness
Morphinone-Based Opioid Receptor Agonist Analgesics
4 Barbituric Acid-Based GABA(A) Receptor Modulators for the Treatment of Sleep Disorder and Epilepsy and as Anesthetics
Phenothiazine-Based Dopamine D2 Antagonists for the Treatment of Schizophrenia
Arylpiperazine-Based 5-HT1A Receptor Partial Agonists and 5-HT2A Antagonists for the Treatment of Autism, Depression, Anxiety, Psychosis, and Schizophrenia
Arylpiperidine-Based Dopamine D2 Antagonists/5-HT2A Antagonists for the Treatment of Autism, Depression, Schizophrenia, and Bipolar Disorder
Dibenzazepine-Based Sodium Channel Blockers for the Treatment of Neuropathic Pain
Cardiovascular Diseases
Dihydropyridine-Based Calcium Channel Blockers for the Treatment of Angina Pectoris and Hypertension
Tetrazole-Based Angiotensin II Type 1 (AT1) Antagonists for the Treatment of Heart Failure and Congestive Hypertension
Thiazide-Based Diuretics for the Treatment of Hypertension and Genitourinary Disorders
Tetrahydropyranone-Based HMG-CoA Reductase Inhibitors for the Treatment of Arterial Hypercholesterolemia
Infectious Diseases
Adenine-Based Reverse Transcriptase Inhibitors as Anti-HIV Agents
Guanine-Based Nucleoside Analogs as Antiviral Agents
Penicillin and Cephalosporin Antibiotics
Oncology
Pyrimidine-Based Kinase Inhibitors in Cancer Chemotherapy
Benzyl Triazole-Based Aromatase Inhibitors for the Treatment of Breast Cancer
Inflammation and Gastrointestinal Diseases
Acetonide-Based Glucocorticoids for the Treatment of Asthma, Skin Inflammation, and Diseases of the Eye
Benzimidazole-Based H+/K+-ATPase Inhibitors for the Treatment of Gastroesophageal Reflux Disease
Metabolic Diseases
Thiazolidinedione-Based Insulin Sensitizers:PPAR-γ Agonists for the Treatment of Type 2 Diabetes