Adeyeye M.C., Brittain H.G. Preformulation solid dosage form development

Informa Healthcare USA, Inc., 2008. — 616 p. — (Drugs and the Pharmaceutical Sciences 178) — ISBN: 9780824758097During the onset of any clinical trial there are many factors and variables to consider. Funding, time restraints, and regulatory agency guidelines are factors that often influence which variables will be studied, leaving other important information out of the study.
Serving as a handbook or stand-alone reference, this text equips those in academia and the pharmaceutical industry with both basic and applied principles for the characterization of drugs, excipients, and products, and deals with the issues relating to predictability, identification, and product development during preformulation stages through Phase I of clinical trials.Preliminary Preformulation
Profiling the Drug Substance
Development of the Ideal Formulation
Beyond Performulation