Batchelor Hannah (ed.) Biopharmaceutics: From Fundamentals to Industrial Practice

Wiley, 2022. — 840 p. — (Advances in Pharmaceutical Technology). — ISBN 9781119678373.In Biopharmaceutics - From Fundamentals to Industrial Practice, distinguished Scientists from the UK's Academy of Pharmaceutical Sciences Biopharmaceutica Focus Group deliver a comprehensive examination of the tools used within the field of biopharmaceutics and their applications to drug development. This edited volume is an indispensable tool for anyone seeking to better understand the field of biopharmaceutics as it rapidly develops and evolves. Beginning with an expansive introduction to the basics of biopharmaceutics and the context that underpins the field, the included resources go on to discuss how biopharmaceutics are integrated into product development within the pharmaceutical industry. Explorations of how the regulatory aspects of biopharmaceutics function, as well as the impact of physiology and anatomy on the rate and extent of drug absorption, follow. Readers will find insightful discussions of physiologically based modeling as a valuable asset in the biopharmaceutics toolkit and how to apply the principles of the field to special populations. Perfect for professionals working in the pharmaceutical and biopharmaceutical industries, Biopharmaceutics - From Fundamentals to Industrial Practice is an incisive and up-to-date resource on the practical, pharmaceutical applications of the field.An Introduction to Biopharmaceutics
Basic Pharmacokinetics
Introduction to Biopharmaceutics Measures
Solubility
Permeability
Dissolution
Biopharmaceutics to Inform Candidate Drug Selection and Optimisation
Biopharmaceutics Tools for Rational Formulation Design
Biopharmaceutic Classification System
Regulatory Biopharmaceutics
Impact of Anatomy and Physiology
Integrating Biopharmaceutics to Predict Oral Absorption Using PBPK Modelling
Special Populations
Inhalation Biopharmaceutics
Biopharmaceutics of Injectable Formulations
Biopharmaceutics of Topical and Transdermal Formulations
Impact of the Microbiome on Oral Biopharmaceutics